Uniprot | Protein | Class | Cohen’s d | p value | Relevant function [associated pathologies] | Refs. |
---|---|---|---|---|---|---|
P00352 | Retinal dehydrogenase 1 | Oxidoreductase | 0.48 | 2.0 × 10−17 | Metabolism processes and oxidation–reduction process [oxidative stress] | [47] |
P51449 | Nuclear receptor ROR gamma | Nuclear hormone receptor | 0.37 | 1.4 × 10−13 | Cytokine-mediated signaling pathways [apoptosis] | [49] |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Transcription factor | 0.36 | 5.5 × 10−13 | Regulation of cellular redox conditions [oxidative stress] | [48] |
Q8IUX4 | DNA dC → dU-editing enzyme APOBEC-3F | Hydrolase | 0.33 | 1.5 × 10−7 | DNA mutators participating in the innate immune system [inducing mutations > apoptosis/necrosis] | [50] |
P11473 (pidgin) | Vitamin D3 receptor | Nuclear hormone receptor | 0.28 | 1.0 × 10−8 | Ca2+ signalling [negative regulation of cell proliferation] | [51] |