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Table 5 The performance of six scoring functions on the DUD-E dataset

From: DLIGAND2: an improved knowledge-based energy function for protein–ligand interactions using the distance-scaled, finite, ideal-gas reference state

Scoring functions LogAUC(%) EF1% EF5% EF10%
DLIGAND2 10.14 6.67 3.31 2.55
AutoDock Vina 9.96 5.12 3.41 2.60
ΔvinaRF20 9.00 6.38 3.41 2.58
DLIGAND 7.61 4.40 2.74 2.23
X-ScoreHM 7.25 4.06 2.68 2.19
ID-Score 2.47 1.61 1.42 1.36
  1. The highest values in each column are labeled italics