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Table 6 Enrichment factor values (EF1%) by DLIGAND2, AutoDock Vina, ΔvinaRF20, DLIGAND, X-ScoreHM, ID-Score on eight protein categories

From: DLIGAND2: an improved knowledge-based energy function for protein–ligand interactions using the distance-scaled, finite, ideal-gas reference state

 

DLIGAND2

Vina

ΔvinaRF20

DLIGAND

X-ScoreHM

ID-Score

Cytochrome P450

6.48

1.93

3.77

5.10

3.59

0.56

GPCR

8.46

2.48

4.17

3.79

1.56

1.49

Ion channel

0.84

4.47

3.48

0.51

0.00

0.83

Kinase

10.01

6.10

7.50

4.41

5.93

1.04

Miscellaneous

6.89

5.65

7.82

6.63

4.46

5.36

Nuclear receptors

5.42

9.14

9.57

4.57

4.01

1.69

Other enzymes

3.23

3.88

4.76

2.52

2.64

1.21

Protease

10.16

4.63

6.99

8.65

5.58

2.57

Average

6.43

4.79

6.01

4.52

3.47

1.84

  1. Italic fonts highlight the highest value in each category