Table 3 Overview of test assays used in hyperparameter search
AID | Compounds tested | Actives | % Actives | Target information | Assay type |
|---|---|---|---|---|---|
834 | 84880 | 123 | 0.14% | Potentiators of clotrimazole | Cell-based |
1236 | 218607 | 799 | 0.37% | Calpain II inhibitors | Biochemical |
1510 | 217964 | 569 | 0.26% | Sphingosine-1-phosphate receptor 4 (S1P4) | Cell-based |
1899 | 302667 | 998 | 0.33% | Hepatitis C Virus (HCV) core protein | Biochemical |
2732 | 218659 | 8240 | 3.77% | DNA damage-inducible transcript 3—CHOP—regulates UPR | Cell-based |
463165 | 305614 | 1365 | 0.45% | Regulator of G-protein signaling 4 isoform 2 (RGS4) | Cell-based |
588621 | 359231 | 887 | 0.25% | Tyrosine-protein phosphatase non-receptor type 5 | Biochemical |
602229 | 362013 | 1281 | 0.35% | Photoreceptor-specific nuclear receptor (NR2E3) | Cell-based |
720543 | 369939 | 2005 | 0.54% | Alpha/beta hydrolase domain containing protein 4 (ABHD4) | Biochemical |
1117267 | 91911 | 1155 | 1.26% | Activators of Transthyretin (TTR) transcription | Cell-based |