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Table 2 Calculated Top2 poisoning IC50 values of test compounds

From: Identifying new topoisomerase II poison scaffolds by combining publicly available toxicity data and 2D/3D-based virtual screening

NSCIC50 (μM)95% CI (μM)
Mitoxantrone3.32.6–4.1
6379923.32.5–4.6
3179217.55.9–9.6
69124012.19.0–16.3
660839\(>100\)NA