From: ACID: a free tool for drug repurposing using consensus inverse docking strategy
Name | Method | Sample seta | Prediction performance | Date of last update | Refs. | |
---|---|---|---|---|---|---|
AUCb | TOP(2%/5%/10%)c | |||||
Similarity comparison based approaches | ||||||
 ChemMapper | 3D similarity approach | 216/7069 | 0.7 | – | Dec 2016 | [25] |
 ChemProt 3.0 | 2D similarity approach | 248/1700 | 0.827 | – | Jan 2015 | [26] |
 HitPick | 1NN similarity search approach | 3430/3116926 | 0.61d | – | May 2013 | [27] |
 SwissTarget-prediction | Combination of 2D and 3D similarity approach | 346/1730 | 0.87 | – | Apr 2014 | [28] |
Docking algorithm based approaches | ||||||
 idTarget | Divide and conquer based docking approach | 1/3/1161, 1/4/1161 | 0.89, 0.91 | – | Aug 2015 | [13] |
 INVDOCK | Inverse docking approach | 2/23/2700 | – | 50%e | May 2001 | [10] |
 TarFisDock | Reverse docking approach | 1/10/37, ··· 1/12/371 | – | 33%/33%/58%, 30%/20%/50% | Aug 2014 | [11] |
 ACID | Consensus inverse docking approach | 51/133/831 | 0.84 | 47%/57%/68% | Dec 2018 |  |