|
Genome
|
ArrayExpress Ê61]
|
A repository of high-throughput functional genomics experiments data
|
|
Cancer Cell Line Encyclopedia (CCLE) [62]
|
A combination of gene expression, chromosomal copy number, and massively parallel sequencing data from human cancer cell lines
|
|
Database for Annotation, Visualization and Integrated Discovery (DAVID) [63]
|
A comprehensive set of functional annotation tools
|
|
Drug versus Disease (DvD) [64]
|
A platform for comparing drug and disease gene expression profiles retrieved from publicly available microarray data resources
|
|
Expression Atlas [65]
|
A tool to explore gene expression data across species and different biological conditions
|
|
Gene Expression Omnibus (GEO) [66]
|
A repository of gene expression profiles
|
|
Gene Set Enrichment Analysis (GSEA)
[67]
|
A tool for interpreting gene expression data
|
|
Gene Signature Database (GeneSigDB) [68]
|
A repository of gene signatures data reported in the literature
|
|
Gene Ontology (GO) [69]
|
A repository of functional genomics
|
|
International Cancer Genome Consortium
[70]
|
A repository of genomic data for many cancer types
|
|
Kyoto Encyclopedia of Genes and Genomes (KEGG) [71]
|
A repository of genome sequencing and high-throughput functional genomics experiments molecular datasets
|
|
Library of Integrated Network-based Cellular Signatures (LINCS)
[72]
|
A catalog of gene expression data and how human cells respond to different genetic and environmental conditions
|
|
Molecular Signature Database (MsigDB) [73]
|
A repository of annotated gene sets and expression profiles
|
|
The Cancer Genome Atlas (TCGA)
[74]
|
A repository of genomic data for more than 30 cancer types
|
|
The Connectivity Map (CMap) [75]
|
A collection of genome-wide transcriptional expression data
|
|
The Universal Protein Resource (UniProt) [76]
|
A repository of protein sequence and functional information
|
|
Phenome
|
ClinicalTrials.gov
[77]
|
A repository of publicly and privately funded clinical studies from around the world
|
|
Side Effect Resource (SIDER)
[78]
|
A repository of adverse drug reactions related to drugs. Information includes drug side effects and side effects classifications
|
|
Chemical structure
|
ChEMBL [79]
|
A repository of drug structural information, such as 3D structures, and abstracted biological activities, extracted from the scientific literature
|
|
Chemicalize
[80]
|
A repository of chemical structure information
|
|
ChemSpider
[81]
|
A repository of chemical structure information
|
|
DrugBank [82]
|
A repository of drug-related information, such as chemical structure for drugs
|
|
Drug Central [83]
|
A repository of drug-related information such as chemical structure and biological activities
|
|
PubChem
[84]
|
A repository of chemical substances and their biological activities
|
|
Protein Data Bank (PDB)
[85]
|
A repository of 3D shape of proteins and nucleic acids information
|
|
SWEETLEAD [36]
|
A repository of 2D and 3D drug chemical structure information, including approved and illegal drugs
|
|
The NCGC Pharmaceutical Collection (NPC)
[86]
|
A collection of chemical structure information related to approved and investigational drugs
|
|
Therapeutic Target Database (TTD)
[87]
|
A repository of drug-related information such as 3D structure, therapeutic class, and clinical development status
|
|
Phenome/genome
|
repoDB
[88]
|
A repository of approved and failed drug-disease associations
|
|
Online Mendelian Inheritance in Man (OMIM)
[89]
|
A repository of human genes and genetic phenotype information
|
|
The Pharmacogenetics and Pharmacogenomics Knowledge Base (PharmGKB) [90]
|
A repository of drug-related information such as drug labels, drug-gene associations, and genotype-phenotype relationships
|
|
Phenome/chemical structure
|
Drugs@FDA Database
[91]
|
A repository of FDA approved drugs and related information
|
