Table 3 Performance comparison between all the consensus approaches implemented, i.e. MaxScore, metamodel, MeanRank and MinRank for the three validation sets
From: MAIP: a web service for predicting blood‐stage malaria inhibitors
consensus | performance metrics | MMV test set | PubChem | St. Jude Screening Set |
|---|---|---|---|---|
MaxScore | ROC AUC score | 0.70 | 0.77 | 0.79 |
Metamodel | 0.67 | 0.69 | 0.82 | |
MeanScore | 0.71 | 0.78 | 0.80 | |
MinRank | 0.64 | 0.77 | 0.73 | |
MaxScore | EF[1 %] | 2.9 | 7.0 | 13.3 |
Metamodel | 3.3 | 7.3 | 10.9 | |
MeanScore | 2.8 | 12.8 | 16.8 | |
MinRank | 2.5 | 7.0 | 11.0 | |
MaxScore | EF[10 %] | 2.4 | 3.0 | 4.6 |
Metamodel | 2.1 | 2.4 | 4.9 | |
MeanScore | 2.3 | 3.0 | 4.3 | |
MinRank | 1.7 | 3.0 | 3.6 |