CHO-K1-A2AR | CHO-K1 | CHO-K1-A2AR vs. CHO-K1 | ||||||
---|---|---|---|---|---|---|---|---|
pEC50a | Rangeb | n | pEC50a | Rangeb | n | Δ pEC50c | Δ Ranged | |
CGS21680 | 8.78 ± 0.2 | 86.33 ± 7.2 | 9 | ND | ND | 4 | – | – |
Cmpd 1 | 7.32 ± 0.2 | 61.14 ± 5.2*** | 8 | 6.49 ± 0.3 | 20.19 ± 2.7 | 4 | 0.83 ± 0.5 | 40.95 ± 7.80 |
Cmpd 2 | 6.29 ± 0.5** | 30.50 ± 8.1 | 6 | 4.85 ± 0.2 | 39.46 ± 3.9 | 4 | 1.44 ± 0.6 | − 8.96 ± 10.6 |
Cmpd 3 | 7.26 ± 0.3** | 28.95 ± 6.3 | 6 | 5.90 ± 0.3 | 18.32 ± 2.3 | 4 | 1.21 ± 0.5 | 10.63 ± 8.70 |
Cmpd 4 | 7.55 ± 0.2 | 37.71 ± 2.9** | 5 | 6.62 ± 0.2 | 18.75 ± 1.7 | 4 | 0.93 ± 0.6 | 18.96 ± 3.60 |
Cmpd 5 | 7.70 ± 0.4** | 27.42 ± 4.4 | 6 | 6.30 ± 0.2 | 19.49 ± 1.7 | 4 | 1.28 ± 2.4 | 7.93 ± 6.1 |
Cmpd 6 | 6.52 ± 0.4 | 33.87 ± 5.3 | 6 | 6.35 ± 0.3 | 31.42 ± 4.6 | 4 | 0.17 ± 0.8 | 2.45 ± 9.9 |