Receptor | EF10 % | EF40 % | AUC | Actives | Inactives | |||
---|---|---|---|---|---|---|---|---|
cali | orig | cali | orig | cali | orig | |||
CFX | 2.24 (0.13) | 1.85 (0.15) | 1.72 (0.08) | 1.46 (0.08) | 0.85 (0.02) | 0.72 (0.03) | 84 (6) | 62 (3) |
D2R | 1.96 (0.31) | 1.34 (0.15) | 1.48 (0.14) | 1.14 (0.12) | 0.68 (0.05) | 0.53 (0.05) | 55 (4) | 104 (6) |
ERK2 | 7.73 (0.43) | 6.26 (0.41) | 2.44 (0.07) | 2.40 (0.09) | 0.97 (0.02) | 0.93 (0.02) | 20 (2) | 151 (7) |
ER | 2.67 (0.25) | 1.91 (0.42) | 2.24 (0.09) | 1.90 (0.16) | 0.95 (0.01) | 0.86 (0.03) | 18 (3) | 32 (4) |
MOR | 1.52 (0.33) | 1.19 (0.31) | 1.36 (0.13) | 1.13 (0.10) | 0.72 (0.05) | 0.59 (0.04) | 45 (4) | 51 (8) |
VEGFR2 | 2.15 (0.12) | 2.18 (0.10) | 1.75 (0.06) | 1.64 (0.06) | 0.86 (0.03) | 0.79 (0.03) | 59 (6) | 70 (4) |
5HT2AR | 1.81 (0.15) | 1.20 (0.18) | 1.54 (0.08) | 1.13 (0.04) | 0.81 (0.02) | 0.58 (0.02) | 77 (5) | 85 (5) |
A2AR | 2.45 (0.13) | 1.66 (0.22) | 1.87 (0.06) | 1.37 (0.05) | 0.86 (0.01) | 0.66 (0.02) | 67 (5) | 109 (6) |
CB1 | 2.09 (0.15) | 1.67 (0.21) | 1.83 (0.08) | 1.32 (0.12) | 0.84 (0.02) | 0.63 (0.03) | 54 (4) | 76 (4) |
M1R | 2.39 (0.24) | 2.33 (0.28) | 1.90 (0.08) | 1.33 (0.11) | 0.87 (0.02) | 0.67 (0.03) | 42 (5) | 73 (6) |
rRNA | 11.50 (2.99) | 0.00 | 2.59 (0.20) | 2.59 (0.20) | 1.00 | 0.86 (0.03) | 1 | 13 (2) |