Table 5 Condition-wise prediction for the FS-LDA model built in CS1
From: QSAR-Co-X: an open source toolkit for multitarget QSAR modelling
SN | Experimental condition element (cj) | Test set | Validation set | ||||
|---|---|---|---|---|---|---|---|
cl | mt | bt | #Instances | %Accuracy | #Instances | %Accuracy | |
1 | Normal- MCF7-neo/Her2 | Non-mutant | PI3K-α | 2 | 100 | 3 | 100 |
2 | Normal-B-cells | Non-mutant | PI3K-δ | 8 | 100 | 12 | 100 |
3 | Normal-BT20 | Non-mutant | PI3K-α | 2 | 100 | 1 | 100 |
4 | Normal-BT474 | Mutant | PI3K-α | 7 | 85.71 | 10 | 90 |
5 | Normal-BT474 | Non-mutant | PI3K-α | 14 | 85.71 | 13 | 84.62 |
6 | Normal-HCC1954 | Non-mutant | PI3K-β | 1 | 100 | 1 | 100 |
7 | Normal-HCT116 | Mutant | PI3K-α | 4 | 100 | 2 | 100 |
8 | Normal-HCT116 | Non-mutant | PI3K-α | 1 | 100 | 3 | 100 |
9 | Normal-HEK293 | Non-mutant | PI3K-β | 1 | 100 | na | na |
10 | Normal-HL60 | Non-mutant | PI3K-α | 3 | 66.67 | 6 | 100 |
11 | Normal-HL60 | Non-mutant | PI3K-β | 5 | 100 | 2 | 50 |
12 | Normal-HL60 | Non-mutant | PI3K-γ | 2 | 100 | na | na |
13 | Normal-HL60 | Non-mutant | PI3K-δ | na | na | 6 | 83.33 |
14 | Normal-HL60 | Non-mutant | PI3K-γ | na | na | 6 | 100 |
15 | Normal-JeKo1 | Non-mutant | PI3K-δ | 4 | 100 | 4 | 100 |
16 | Normal-MDA-MB-453 | Mutant | PI3K-α | 4 | 100 | 5 | 100 |
17 | Normal-MDA-MB-468 | Non-mutant | PI3K-β | 3 | 100 | 10 | 100 |
18 | Normal-PBMC | Non-mutant | PI3K-δ | na | na | 1 | 0 |
19 | Normal-PC3 | Non-mutant | PI3K-α | 7 | 100 | 12 | 91.67 |
20 | Normal-PC3 | Non-mutant | PI3K-β | 2 | 100 | na | na |
21 | Normal-PC3 | Non-mutant | PI3K-γ | 1 | 100 | na | na |
22 | Normal-Ramos | Non-mutant | PI3K-δ | 1 | 100 | na | na |
23 | Normal-Ri-1 | Non-mutant | PI3K-δ | na | na | 5 | 80 |
24 | Normal-THP1 | Non-mutant | PI3K-β | 1 | 0 | na | na |
25 | Normal-THP1 | Non-mutant | PI3K-δ | 3 | 100 | 6 | 66.67 |
26 | Normal-THP1 | Non-mutant | PI3K-γ | 1 | 100 | na | na |
27 | Normal-U2OS | Non-mutant | PI3K-α | 2 | 100 | 3 | 100 |
28 | Normal-U87MG | Non-mutant | PI3K-α | 7 | 100 | 15 | 86.67 |
29 | Normal-U937 | Non-mutant | PI3K-δ | 1 | 100 | na | na |
30 | PTEN-deficient-MDA-MB-468 | Non-mutant | PI3K-β | 5 | 100 | 7 | 100 |
31 | PTEN-deficient-PC3 | Non-mutant | PI3K-β | 10 | 100 | 19 | 89.47 |
32 | PTEN-deficient-U87MG | Non-mutant | PI3K-α | 3 | 100 | na | na |
33 | PTEN-Null-MDA-MB-468 | Non-mutant | PI3K-β | 8 | 100 | 8 | 100 |
34 | PTEN-Null-PC3 | Non-mutant | PI3K-α | 1 | 100 | na | na |