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Table 5 The number of top-1, top-10, and failure predictions in the benchmark set for five target prediction servers

From: LigTMap: ligand and structure-based target identification and activity prediction for small molecular compounds

  SwissTargetPrediction SEA SuperPred HitPick LigTMap
Top 1 Top 10 Fail Top 1 Top 10 Fail Top 1 Top 10 Fail Top 1 Top 10 Fail Top 1 Top 10 Fail
Beta-secretase 16 19 0 17 19 0 9 19 0 6 6 13 15 19 0
Bromodomain 17 19 0 19 19 0 0 0 19 0 0 19 14 18 1
Kinase 10 13 5 1 18 0 0 0 18 10 10 8 3 13 5
Carbonic anhydrase 8 9 7 4 8 8 6 7 8 1 5 8 13 16 0
Ligase 0 0 5 0 0 5 0 0 5 0 0 5 0 0 5
Total 51 60 17 41 64 13 15 27 50 17 24 53 45 66 11
(%) 66 78 22 53 83 17 19 35 65 22 31 69 59 86 14