Table 5 The number of top-1, top-10, and failure predictions in the benchmark set for five target prediction servers
| Â | SwissTargetPrediction | SEA | SuperPred | HitPick | LigTMap | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Top 1 | Top 10 | Fail | Top 1 | Top 10 | Fail | Top 1 | Top 10 | Fail | Top 1 | Top 10 | Fail | Top 1 | Top 10 | Fail | |
Beta-secretase | 16 | 19 | 0 | 17 | 19 | 0 | 9 | 19 | 0 | 6 | 6 | 13 | 15 | 19 | 0 |
Bromodomain | 17 | 19 | 0 | 19 | 19 | 0 | 0 | 0 | 19 | 0 | 0 | 19 | 14 | 18 | 1 |
Kinase | 10 | 13 | 5 | 1 | 18 | 0 | 0 | 0 | 18 | 10 | 10 | 8 | 3 | 13 | 5 |
Carbonic anhydrase | 8 | 9 | 7 | 4 | 8 | 8 | 6 | 7 | 8 | 1 | 5 | 8 | 13 | 16 | 0 |
Ligase | 0 | 0 | 5 | 0 | 0 | 5 | 0 | 0 | 5 | 0 | 0 | 5 | 0 | 0 | 5 |
Total | 51 | 60 | 17 | 41 | 64 | 13 | 15 | 27 | 50 | 17 | 24 | 53 | 45 | 66 | 11 |
(%) | 66 | 78 | 22 | 53 | 83 | 17 | 19 | 35 | 65 | 22 | 31 | 69 | 59 | 86 | 14 |