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Table 8 Comparison of various features of target prediction servers

From: LigTMap: ligand and structure-based target identification and activity prediction for small molecular compounds

Server feature SEA SwissTarget Prediction SuperPred HitPick LigTMap
Target scope
 Predict human targets Yes Yes Yes Yes Yes
 Predict non-human (viral and bacterial) targets No Yes (few) No No Yes
Prediction
 Support input of multiple compounds No No No Yes Yes
 Target name Yes Yes Yes Yes Yes
 Target PDB No No Yes No Yes
 Biological activity No No No No Yes
 Binding mode No No No No Yes
 External links to target related information ZINC Uniprot, GeneCard Uniprot, BindingDB, RefSeq, etc GeneCard PDB