Fig. 9
From: “Molecular Anatomy”: a new multi-dimensional hierarchical scaffold analysis tool
Visualization of the most populated cluster, starting from the network visualization of the 816 COX-2 inhibitors shown in Fig. 8a, corresponding to the 142 COX-2 inhibitors having the same basic wireframe, zoomed in the Figure. It is also possible to identify the molecular frameworks with more connection in the network and more representative of the active molecules (violet bordered)