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Table 1 Activity thresholds for 26,092 commercial compounds tested at 10 μM concentration against HDAC7, classified on the basis of enzyme activity percent of inhibition

From: “Molecular Anatomy”: a new multi-dimensional hierarchical scaffold analysis tool

Activity class N. of compounds % of inhibition
Inactive 23,750  < 19
Weak 2141 19–33
Moderate 144 33–50
Strong 37 50–80
Very strong 20  > 80