Table 3 Target list used for model validation
From: QPHAR: quantitative pharmacophore activity relationship: method and validation
Target | UniProt ID | CHEMBL ID |
|---|---|---|
Alpha-2a adrenergic receptor | P08913 | CHEMBL1867 |
Tyrosine-protein kinase ABL | P00519 | CHEMBL1862 |
Acetylcholinesterase | P22303 | CHEMBL220 |
Androgen receptor | P10275 | CHEMBL1871 |
Serine/threonine-protein kinase Aurora-A | O14965 | CHEMBL4722 |
Serine/threonine-protein kinase B-raf | P15056 | CHEMBL5145 |
Cannabinoid CB1 receptor | P21554 | CHEMBL218 |
Carbonic anhydrase II | P00918 | CHEMBL205 |
Caspase-3 | P42574 | CHEMBL2334 |
Thrombin | P00734 | CHEMBL204 |
Cyclooxygenase-1 | P23219 | CHEMBL221 |
Cyclooxygenase-2 | P35354 | CHEMBL230 |
Dihydrofolate reductase | P00374 | CHEMBL202 |
Dopamin D2 receptor | P14416 | CHEMBL217 |
Norepinephrine transporter | P23975 | CHEMBL222 |
Epidermal growth factor receptor erbB1 | P00533 | CHEMBL203 |
Estrogen receptor alpha | P03372 | CHEMBL206 |
Glucocorticoid receptor | P04150 | CHEMBL2034 |
Glycogen synthase kinase-3 beta | P49841 | CHEMBL262 |
HERG | Q12809 | CHEMBL240 |
Tyrosine-protein kinase JAK2 | O60674 | CHEMBL2971 |
Tyrosine-protein kinase LCK | P06239 | CHEMBL258 |
Monoamine oxidase A | P21397 | CHEMBL1951 |
Mu opioid receptor | P35372 | CHEMBL233 |
Vanilloid receptor | Q8NER1 | CHEMBL4794 |