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Fig. 1 | Journal of Cheminformatics

Fig. 1

From: Investigation of pharmacological mechanism of natural product using pathway fingerprints similarity based on “drug-target-pathway” heterogenous network

Fig. 1

Comparison of targets of XYPI, GCs and NSAIDs. A Bubble chart of functional enrichment of potential XYPI targets. The X axis is the enrichment score for each term using the whole genome as background, the Y axis is the negative log10(FDR), and the node size is related to the targets matched in this term. B Venn diagram of the drug targets of XYPI, GCs and NSAIDs. C, D Hierarchical clustering of XYPI, GCs (green) and NSAIDs (blue) based on target similarity (C) and pathway fingerprint similarity based on GOBP, Reactome, WikiPathways (D)

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Journal of Cheminformatics

ISSN: 1758-2946

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