Fig. 1

MAP4 TMAP of the 60 thousand selected COCONUT entries. The maps are colored according to a molecular weight MW in Da, b fraction of sp3 carbon atoms Fsp3, c calculated octanol:water partition coefficient AlogP, d COCONUT annotated origin, e presence of a glycoside (blue) or peptide (green) substructure, or both (magenta), f prioritized categories: glycosides (entries containing a glycoside substructure, blue) > peptides (entries containing a peptide substructure, cyan) > high MW (green) > high Fsp3 (yellow) > low Fsp3 (orange) > low MW (red). Entries not belonging to any category are reported in gray. All maps are accessible in an interactive format at https://tm.gdb.tools/map4/coconut_tmap/