Table 2 Cluster name, number of genes, and COG categories for M. Tuberculosis gene clusters
Clusters (C) | Cluster name | # Gene | COG categories |
|---|---|---|---|
C1 | Tricarboxylic acid cycle and central carbon metabolism | 9 | O; C; E; F |
C2 | Translation and tRNA synthesis | 11 | M; J |
C3 | Non-aromatic amino acid biosynthesis | 13 | E; H |
C4 | Aromatic amino acid biosynthesis | 5 | E; H |
C5 | Stress protection and pathway equilibration | 9 | D; O; T; U; E; G; P |
C6 | tRNA and nascent polypeptide modification | 10 | M; T; J; E; F; S |
C7 | Folate and purine metabolism | 5 | C; E; F; H |
C8 | DNA replication and transcription regulation | 9 | K; L; H; I; O |
C9 | Lipid and lipid cofactor synthesis | 11 | F; H; I; Q |
C10 | Glycolysis and gluconeogenesis | 8 | C; E; F; G |
C11 | Peptidoglycan and precursor synthesis | 6 | D; M; G |
C12 | Purine and pyrimidine metabolism | 8 | M; F; G |
C13 | Porphyrin-compound synthesis | 5 | H |