Table 8 The detailed comparison results (Accuracy) between models using different methods
From: Machine learning to predict metabolic drug interactions related to cytochrome P450 isozymes
Dataset | Methods | 1A2_In | 2C9_In | 2C19_In | 2D6_In | 3A4_In | 2C9_Sub | 2D6_Sub | 3A4_Sub |
|---|---|---|---|---|---|---|---|---|---|
Multi-validation | DNN | 0.293 | 0.345 | 0.471 | 0.712 | 0.506 | – | – | – |
Ours | 1.000 | 1.000 | 1.000 | 0.856 | 0.915 | – | – | – | |
NCATS | SB | – | 0.614 | – | 0.550 | 0.653 | 0.618 | 0.607 | 0.663 |
Ours | – | 0.662 | – | 0.629 | 0.664 | 0.632 | 0.608 | 0.547 |