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Table 9 The most frequently 10 drugs predicted to cause DDIs when interacting with other drugs

From: Machine learning to predict metabolic drug interactions related to cytochrome P450 isozymes

Drugs Interact with No. of predicted DDIs
Cidofovir CYP2C9, CYP3A4 455
Alendronate CYP1A2, CYP3A4 444
Trifluridine CYP2D6, CYP3A4 442
Promazine CYP2C19, CYP2D6, CYP3A4 439
Vinblastine CYP3A4 424
Chloropyramine CYP2C19, CYP2D6 397
Citalopram CYP2C19, CYP2D6, CYP3A4 396
Clarithromycin CYP3A4 384
Vincristine CYP3A4 384
Nitrendipine CYP3A4 384