Table 9 The most frequently 10 drugs predicted to cause DDIs when interacting with other drugs
From: Machine learning to predict metabolic drug interactions related to cytochrome P450 isozymes
Drugs | Interact with | No. of predicted DDIs |
|---|---|---|
Cidofovir | CYP2C9, CYP3A4 | 455 |
Alendronate | CYP1A2, CYP3A4 | 444 |
Trifluridine | CYP2D6, CYP3A4 | 442 |
Promazine | CYP2C19, CYP2D6, CYP3A4 | 439 |
Vinblastine | CYP3A4 | 424 |
Chloropyramine | CYP2C19, CYP2D6 | 397 |
Citalopram | CYP2C19, CYP2D6, CYP3A4 | 396 |
Clarithromycin | CYP3A4 | 384 |
Vincristine | CYP3A4 | 384 |
Nitrendipine | CYP3A4 | 384 |