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Fig. 5 | Journal of Cheminformatics

Fig. 5

From: BitterMatch: recommendation systems for matching molecules with bitter taste receptors

Fig. 5

Matching intensely bitter drugs to human TAS2Rs. Very bitter predicted drugs from DrugBank (version 5.1.5) were assigned to human TAS2Rs using BitterMatch. The proportion of drugs that were predicted to activate each receptor represented in red. In grey- the proportion (hit rate) of known ligands per receptor. Normalization for the drugs was performed by dividing the number of drugs predicted to activate the receptor by the total number of drugs. The hit rate was calculated by dividing the number of ligands by the number of compounds that were tested for each specific receptor

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