Fig. 2
Screenshots of FPocketWeb applied to TEM-1. A TEM-1 when the ligand FTA is bound in the allosteric site (PDB ID: 1PZP). The top-ranked pocket, shown in surface representation, encompasses both the allosteric and orthosteric pockets, marked with a dagger and double dagger, respectively. B TEM-1 when penicillin G (open form) is bound in the orthosteric site (PDB ID: 1FQG). The fifth-ranked pocket, shown in surface representation, corresponds to the orthosteric pocket (double dagger). The allosteric pocket was not detected because it is collapsed.