Fig. 2

Dissection of scaffolds into building blocks. A Flucloxacillin with its Murcko framework marked in blue. B Rings of flucloxacillin marked in blue. It is important to note that the fused ring system on the right would be split into its two constituting rings in the structure set returned by the described routine of Scaffold Generator. C Linkers of flucloxacillin marked in blue. D Terminal side chains of flucloxacillin marked in blue