PDB code | Protein | Res (Ã…) | Ligand | Structure Ref. |
---|---|---|---|---|
1AI5 | Penicillin acylase | 2.4 | m-nitrophenylacetic acid | [24] |
1AJP | Penicillin acylase | 2.3 | 2,5-dihydroxyphenylacetic acid | [24] |
1AMW | Heat shock protein 90 | 1.9 | ADP | [25] |
1BGQ | Heat shock protein 90 | 2.5 | radicicol | [26] |
1CBR | Retionic acid binding protein | 2.9 | retinoic acid | [27] |
1D3Q | Human thrombin | 2.9 | benzo [b]thiophene derivative | [28] |
1D3T | Human thrombin | 3.0 | benzo [b]thiophene derivative | [28] |
1DWB | a-Thrombin | 3.2 | benzamidine | [29] |
1FLR | Immunoglobulin | 1.9 | fluorescein | [30] |
1GNI | Human serum albumin | 2.4 | oleic acid | [31] |
1HVJ | HIV-1 Protease | 2.0 | A78791 | [32] |
1HVR | HIV-1 Protease | 1.8 | XK263 | [33] |
1K4G | tRNA-guanine transglycosylase | 1.7 | quinazoline derivative | [34] |
1KV1 | p38 MAP kinase | 2.5 | pyrazol derivative | [35] |
1LIF | Adipocyte lipid-binding protein | 1.6 | stearic acid | [36] |
1M0N | Dialkylglycine decarboxylase | 2.2 | 1-aminocyclo-pentanephosphonate | [37] |
1M0Q | Dialkylglycine decarboxylase | 2.0 | S-1-amino-ethanephosphonate | [37] |
1OLU | Branched-chain alpha-ketoacid dehydrogenase kinase | 1.9 | thiamin diphosphate | [38] |
1Q8T | cAMP-dependent protein kinase | 2.0 | (R)-trans-4-(1-aminoethyl)-n-(4-pyridyl) cyclohexanecarboxamide | [39] |
1RBP | Retinol-binding protein | 2.0 | retinol | [40] |
1S39 | tRNA-guanine transglycosylase | 2.0 | 2-aminoquinazolin-4(3H)-one | [41] |
1U33 | Alpha-amylase | 2.0 | 5-trihydroxy-6-hydroxymethyl-piperidin-2-one | [42] |
1ULB | Purine nucleoside phosphorylase | 2.8 | guanine | [43] |
1UWT | Beta-glycosidase | 2.0 | D-galactohydroximo-1,5-lactam | [44] |
1X8R | 3-Phosphoshikimate 1-carboxyvinyltransferase | 1.5 | phosphonate analogue | [45] |
1XD1 | Alpha-amylase | 2.2 | acarbose derived hexasaccharide | [46] |
1YDT | cAMP-dependent protein kinase | 2.3 | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline | [47] |
1ZC9 | Dialkylglycine decarboxylase | 2.0 | pyridoxamine 5-phosphate | [48] |
2ACK | Acetylcholinesterase | 2.4 | edrophonium ion | [49] |
2BAJ | p38alpha Map kinase | 2.3 | pyrazol derivative | [50] |
2BAK | p38alpha Map kinase | 2.2 | nicotinamid derivative | [50] |
2CEQ | Beta-glycosidase | 2.1 | glucoimidazole | [51] |
2CET | Beta-glycosidase | 2.0 | phenethyl-substituted glucoimidazole | [51] |
2CGR | Immunoglobulin | 2.2 | N-trisubstituted guanidine | [52] |
2CPP | Cytochrome P-450cam | 1.6 | camphor | [53] |
2D3U | RNA-dependent RNA polymerase | 2.0 | non-nucleoside analogue inhibitor I | [54] |
2D3Z | RNA-dependent RNA polymerase | 1.8 | non-nucleoside analogue inhibitor II | [54] |
2FDP | Beta-secretase | 2.5 | amino-ethylene inhibitor | [55] |
2G94 | Beta-secretase | 1.9 | valinamide derivative | [56] |
2GBP | D-galactose/D-glucose binding protein | 1.9 | glucose | [57] |
2IFB | Fatty-acid-binding protein | 2.0 | palmitic acid | [58] |
2IWX | Heat shock protein 82 | 1.5 | synthetic macrolactone | [59] |
2J77 | Beta-glycosidase | 2.1 | deoxynojirimycin | [Gloster, to be published] |
2J78 | Beta-glycosidase | 1.7 | gluco-hydroximolactam | [Gloster, to be published] |
2QFU | 3-Phosphoshikimate 1-carboxyvinyltransferase | 1.6 | shikimate-3-phosphate | [60] |
2QWB | Neuraminidase | 2.0 | sialic acid | [61] |
2QWD | Neuraminidase | 2.0 | 4-amino-Neu5Ac2en | [61] |
2R04 | Rhinovirus 14 coat protein | 3.0 | W71, antiviral agent | [62] |
2XIS | Xylose isomerase | 1.6 | D-xylitol | [63] |
2YPI | Triose phosphate isomerase | 2.5 | 2-phosphoglycolic acid | [64] |
3PTB | b-Trypsin | 1.8 | benzamidine | [65] |
4HMG | Hemagglutinin | 3.0 | sialic acid | [66] |
7ABP | Arabinose-binding protein | 1.7 | fucose | [67] |