Table 3 Ranking of top-50 targets by numbers of compounds and documents.

1

F10

2159

42869

690

2

CNR1

1268

29658

578

3

KDR

3791

27661

350

4

MAPK14

1432

24568

309

5

DRD3

1814

23405

508

6

F2

2147

22853

768

7

HRH3

11255

22748

407

8

TACR1

6869

21908

626

9

MMP13

4322

20590

315

10

CNR2

1269

19712

464

11

MMP1

4312

17525

394

12

ADORA2A

135

17181

532

13

EGFR

1956

16581

445

14

SLC6A4

6532

16571

403

15

MMP9

4318

16537

344

16

HTR6

3362

16457

504

17

MMP2

4313

16405

310

18

HTR2C

3358

15945

475

19

CRHR1

1394

15550

222

20

MC4R

4160

15084

299

21

HTR2A

3356

14622

509

22

NPY5R

4889

14547

216

23

CCR3

1232

14136

114

24

OPRM1

4988

13394

466

25

DPP4

1803

13057

308

26

REN

5972

12894

438

27

CALCRL

10203

12615

137

28

CTSS

1520

12426

177

29

CHRM3

1131

12398

412

30

CCR2

729230

12208

160

31

DRD2

1813

12050

564

32

MET

4233

11745

118

33

ADORA1

134

11644

480

34

GSK3B

2932

11283

198

35

CCR5

1234

11179

197

36

CXCR2

3579

10851

183

37

SRC

6714

10838

282

38

MCHR1

2847

10821

209

39

EDNRA

1909

10769

260

40

NR3C1

2908

10687

199

41

EDNRB

1910

10601

239

42

HTR1A

3350

10015

627

43

OPRK1

4986

9690

375

44

TACR2

6865

9676

301

45

SLC6A2

6530

9671

272

46

ADORA3

140

9533

457

47

OPRD1

4985

9500

394

48

HSD11B1

3290

9334

151

49

ELANE

1991

9173

308

50

TRPV1

7442

8988

150