Table 1 DUD data sets
| Â | Filtered sets | Original sets | ||
|---|---|---|---|---|
target | actives | decoy | actives | decoys |
ACE | 46 | 1796 | 49 | 1797 |
AChE | 99 | 3859 | 107 | 3891 |
ADA | 23 | 927 | 39 | 927 |
ALR2 | 26 | 986 | 26 | 995 |
AmpC | 21 | 786 | 21 | 786 |
AR | 68 | 2848 | 79 | 2854 |
CDK2 | 47 | 2070 | 72 | 2074 |
COMT | 11 | 468 | 11 | 468 |
COX-1 | 23 | 910 | 25 | 911 |
COX-2 | 212 | 12606 | 426 | 13289 |
DHFR | 190 | 8350 | 410 | 8366 |
EGFr | 365 | 10303 | 475 | 15996 |
ERagonist | 63 | 2568 | 67 | 2570 |
ERantagonist | 18 | 1058 | 39 | 1448 |
FGFr1 | 71 | 3462 | 120 | 4550 |
FXa | 64 | 1633 | 146 | 5743 |
GART | 8 | 155 | 40 | 879 |
GPB | 52 | 2135 | 52 | 2947 |
GR | 32 | 2585 | 78 | 2947 |
HIVPR | 4 | 9 | 62 | 2038 |
HIVRT | 34 | 1494 | 43 | 1519 |
HMGR | 25 | 1423 | 35 | 3478 |
HSP90 | 23 | 975 | 37 | 979 |
InhA | 57 | 2707 | 86 | 3266 |
MR | 13 | 636 | 15 | 634 |
NA | 49 | 1713 | 49 | 1874 |
P38 | 137 | 6779 | 454 | 9140 |
PARP | 31 | 1350 | 35 | 1351 |
PDE5 | 26 | 1697 | 88 | 1977 |
PDGFrb | 124 | 5603 | 170 | 5980 |
PNP | 25 | 1036 | 49 | 1036 |
PPARγ | 6 | 40 | 85 | 3117 |
PR | 22 | 920 | 27 | 1041 |
RXR α | 18 | 575 | 20 | 750 |
SAHH | 33 | 1346 | 33 | 1346 |
SRC | 98 | 5679 | 159 | 6319 |
thrombin | 23 | 1148 | 72 | 2456 |
TK | 22 | 891 | 22 | 891 |
trypsin | 9 | 718 | 49 | 1664 |
VEGFr2 | 48 | 2712 | 88 | 2906 |