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Table 1 Basic features of software tools for channel identification

From: MOLE 2.0: advanced approach for analysis of biomacromolecular channels

Features Software
  MOLE 2.0 MOLE 1.4 MolAxis CAVER 2.0 CAVER 3.0
Input and output Command line interface Yes Yes Yes Yes Yes
GUI Yes Web Web No No
Suggested start points from CSA Yes Yes No No No
Automatic suggestion of start points Yes No Yes No No
Possibility to set end point Yes No No No No
PyMOL export Yes Yes No Yes Yes
PyMOL plugin Yes Yes No Yes Yes
Settings of calculation Number of parameters 9 9 11 8 35
Adjustable surface of a molecule Yes No Limited No Yes
Channel filtering Yes No Limited No Yes
Cavity computation Yes No No No No
  Computation of physicochemical properties Yes No No No No