Figure 2

Histogram plots comparing the calculated physicochemical properties of a reference dataset of compounds with known subcellular localization features (top row) in relation to the library of 1,344 styryl molecules analyzed in this study (bottom row). A) Molecular weight; B) Radius of gyration; C) Logarithm of the octanol:water partition coefficients (logP); D) Fraction of rotatable bonds; E) Number of hydrogen bond acceptors.