Table 4 MUV structure activity classes
From: Condorcet and borda count fusion method for ligand-based virtual screening
Activity index | Activity class | Pair-wise similarity |
|---|---|---|
466 | S1P1 rec. (agonists) | 0.445 |
548 | PKA (inhibitors) | 0.430 |
600 | SF1 (inhibitors) | 0.445 |
644 | Rho-Kinase2 (inhibitors) | 0.416 |
652 | HIV RT-RNase (inhibitors) | 0.398 |
689 | Eph rec. A4 (inhibitors) | 0.449 |
692 | SF1 (agonists) | 0.365 |
712 | HSP 90 (inhibitors) 30 | 0.413 |
713 | ER-a-Coact. Bind. (inhibitors) | 0.389 |
733 | ER-b-Coact. Bind. (inhibitors) | 0.352 |
737 | ER-a-Coact. Bind. (potentiators) | 0.502 |
810 | FAK (inhibitors) | 0.425 |
832 | Cathepsin G (inhibitors) | 0.435 |
846 | FXIa (inhibitors) | 0.532 |
852 | FXIIa (inhibitors) | 0.492 |
858 | D1 rec. (allosteric modulators) | 0.400 |
859 | M1 rec. (allosteric inhibitors) | 0.386 |