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Table 4 MUV structure activity classes

From: Condorcet and borda count fusion method for ligand-based virtual screening

Activity index Activity class Pair-wise similarity
466 S1P1 rec. (agonists) 0.445
548 PKA (inhibitors) 0.430
600 SF1 (inhibitors) 0.445
644 Rho-Kinase2 (inhibitors) 0.416
652 HIV RT-RNase (inhibitors) 0.398
689 Eph rec. A4 (inhibitors) 0.449
692 SF1 (agonists) 0.365
712 HSP 90 (inhibitors) 30 0.413
713 ER-a-Coact. Bind. (inhibitors) 0.389
733 ER-b-Coact. Bind. (inhibitors) 0.352
737 ER-a-Coact. Bind. (potentiators) 0.502
810 FAK (inhibitors) 0.425
832 Cathepsin G (inhibitors) 0.435
846 FXIa (inhibitors) 0.532
852 FXIIa (inhibitors) 0.492
858 D1 rec. (allosteric modulators) 0.400
859 M1 rec. (allosteric inhibitors) 0.386