Figure 5

Dependency of term C on R for calculating Be¹⁰-points. The depicted plot shows the combination of two sigmoid functions to reflect the increasing danger with increasing ratio of batch concentration to the toxicological minimum limit concentration (e.g. TLV or LD50). In region 1 (i.e. working below the limit concentration) the plot starts very flat. The slope rises in region 2 (working at or a little over the limit concentration) and further rises strongly in region 3 (working far over the limit concentration) until it approaches a score of almost 10000 points at the 10-fold excess. See text in section ‘Be¹⁰-Points’ for more details.