Figure 8From: Atom-Atom-Path similarity and Sphere Exclusion clustering: tools for prioritizing fragment hits Docking results. (a) Model of C12M01 bound in the MAP4K4 binding site with extended P-loop conformation. (b) Model of C12M02 bound in the pocket with folded P-loop conformation. (c) Overlay of docking poses of C12M01 and C12M02. (d) Overlay of the docking pose of C12M02 and the crystallographic pose of an amino quinazoline ligand in 4OBO.Back to article page