Fig. 9

Depositor statistics of invalid atom types (r = 0) in PubChem Substance. Top-10 depositors of substances containing atom types that do not pass the PubChem valence list. Investigated atom types were limited to the 2,727 organic (H, C, N, O, F, P, S, Cl, Br, I) atom types that are connected only to other organic atoms, in order to purposely exclude ‘invalid’ atom types that could result from organic/metal interactions being represented as covalent bonds.