Fig. 3From: A reliable computational workflow for the selection of optimal screening librariesEnrichment curves obtained from the similarity analysis for six of the 25 fingerprints considered in this work (see Additional file 1: Tables S4–S9 for details on all fingerprints). a–f refer, respectively to Carbinoxamine, a ligand of the Histamine H1 receptor (CMC), fluocinolone acetonide, a ligand of the glucocorticiod receptor (CMC), lymecycline, an antibiotic drug (Drug Bank), haloperidol, an antipsychotic drug (Drug Bank), CHEMBL488890, a ligand of the Melanin-concentrating hormone receptor 1 and CHEMBL14759 a ligand of the human immunodeficiency virus type 1 protease as the reference (known active) compounds. For fingerprints in which the Tanimoto coefficient levels off before covering 100 % of the target there is no way to differentiate the compounds from one another hence these fingerprints are displayed as straight lines from the point where the coefficients levels offBack to article page