|
Scaffold of well-known toxin toxoflavin present in Burkholderia glumae, it was also previously identified by workers at Abbott using the ALARM NMR assay as a thiol trap and cause of false positives in HTS [37]
|
|
Scaffold a 6H-anthra[1,9-cd]isoxazol-6-one is known to react with DMSO acting as a nucleophile and undergoes N–O cleavage of the isoxazole ring to form the ring opened anthraquinone, a species known to form covalent adducts [38]
|
|
Scaffold likely made by reaction of orthophenylene diamine with the corresponding furanyl alpha diketone. It could be a false positive if contaminated with the furanyl alpha diketone. It has only weak metal coordinating activity
|
|
Scaffold the synthesis of the tricyclic scaffold by a malononitrile cyclization with a 2-amino-3-formyl-4-oxo-4H-pyrido[1,2-a] pyrimidine suggests that the scaffold in this series may be susceptible to Michael attack at what was originally the formyl precursor carbon
|
|
Scaffold is reported to possess strong fluorescence, UV absorbance as well as strong mutagenic activity [39]. The phenyl-2-(2H-benzotriazol-2-yl) scaffold is also found in the photostabilizer Tinuvin P
|
