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Table 2 Comparison of the top1 and top3 success rates for various methods using 48 bound/unbound structures

From: bSiteFinder, an improved protein-binding sites prediction server based on structural alignment: more accurate and less time-consuming

Method Bounda Unboundb
Top1 (%) Top3 (%) Top1 (%) Top3 (%)
bSiteFinder 93.8 98.7 85.4 95.8
LISEc 92 96 81 92
MPK2c 85 96 80 94
VICEc 85 94 83 90
MPK1c 83 96 75 90
DoGSitec 83 92 71 92
Fpocketc 83 92 69 94
LIGSITECSc 81 92 71 85
LIGSITECSCc 79 71
MSPocketc 77 94 75 88
POCASAc 77 90 75 92
Q-SiteFinderc 75 90 52 75
PocketPickerc 72 85 69 85
CASTc 67 83 58 75
PASSc 63 81 60 71
SURFNETc 54 78 52 75
  1. aThe MCC scores of the Top1 and Top3 are 0.95 and 0.97 respectively with 48 bound structures
  2. bThe MCC scores of the Top1 and Top3 are 0.72 and 0.75 respectively with 48 unbound structures
  3. cThe success rates of these methods were taken from Xie and Hwang [32]