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Table 1 Publicly accessible web-based target prediction tools

From: The polypharmacology browser: a web-based multi-fingerprint target prediction tool using ChEMBL bioactivity data

Website Similarity method Database Ref.
www.gdb.unibe.ch 10 different fingerprints ChEMBL 21 This work
http://www.pharmaexpert.ru/passonline/ Multilevel neighbourhoods of atoms (MNA) descriptors WDI and ACD [10]
http://www.dddc.ac.cn/tarfisdock/ Docking PDTD [12]
http://sea.bkslab.org ECfp4 CHEMBL 16, WOMBAT, MDDR and StarLite [14]
http://59.78.96.61/pharmmapper/ Receptor-based pharmacophore models TargetBank, DrugBank, BindingDB, PDTD [17]
https://cpi.bio-x.cn/drar/ Docking PDB, DrugBank [18]
www.cbligand.org/TargetHunter ECfp6, ECfp4 and Openbabel FP2 ChEMBL 11 and PubChem bioassay [22]
http://lilab.ecust.edu.cn/chemmapper/ Openbabel FP2, MACSS, SHAFT and USR ChEMBL 14, BindingDB, DrugBank, KEGG and PDB [23]
http://mips.helmholtz-muenchen.de/proj/hitpick Circular fingerprint FCFP STITCH [24]
http://modlab-cadd.ethz.ch/software/spider/ CATS and MOE physiochemical descriptors COBRA [26]
www.swisstargetprediction.ch Openbabel FP2 and Electroshape descriptors ChEMBL 16 [28]
http://prediction.charite.de/index.php ECfp4 ChEMBL, SuperTarget and BindingDB [29]
www.dddc.ac.cn/tarpred ECfp4 BindingDB [33]
http://potentia.cbs.dtu.dk/ChemProt Sfp ChEMBL 14, BindingDB, DrugBank, PharmGKB, PubChem bioassay, WOMBAT, IUPHAR, CTD and STITCH [37]