Fig. 5

Screening efficiencies of different cartridges plotted as false positive rate and precision. OrChem values are not plotted because they are the same as those of Sachem/OrChem, which uses the same fingerprint. a Comparison of screening FPR for all queries in all cartridges; lower is better. Plotted values are the percent of queries from the query set that have a higher FPR when executed in given cartridge. For example, in Sachem/Lucy only \(5\%\) of the queries have FPR worse than \(10^{-3}\), and just under \(80\%\) of the queries have negligible FPR (less than \(10^{-5}\)). b Same comparison for different parameters of Sachem/Lucy. The solid red line indicates the default parameters of Sachem/Lucy. c Comparison of the screening precision of all cartridges; higher is better. Plotted values are the percent of queries in the corresponding cartridge that have at least the given precision. d Same comparison for different variants of Sachem/Lucy