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Table 2 Confusion matrix for a pair of interaction fingerprints, containing the frequencies of common on bits (a), common off bits (d), and exclusive on bits for Complex 1 (b) and Complex 2 (c)

From: Life beyond the Tanimoto coefficient: similarity measures for interaction fingerprints

p = a + b + c + d Complex 2
1 (interaction present) 0 (interaction absent)
Complex 1
1 (interaction present) a b
0 (interaction absent) c d