From: Life beyond the Tanimoto coefficient: similarity measures for interaction fingerprints
Short name | Name | Uniprot | Protein family | PDB code | No. actives | No. inactives | |
---|---|---|---|---|---|---|---|
1 | ACE | Angiotensin-converting enzyme | P12821 | Hydrolase | 4CA5 | 49 | 1727 |
2 | ACHE | Acetylcholine esterase | P22303 | Hydrolase | 4M0F | 105 | 3708 |
3 | ALR2 | Aldose reductase | P15121 | Oxidoreductase | 4XZH | 26 | 917 |
4 | AR | Androgen receptor agonists | P10275 | Transcription factor | 4OEA | 64 | 2234 |
5 | CDK2 | Cyclin dependent kinase 2 | P24941 | Protein kinase | 1AQ1 | 48 | 1763 |
6 | COMT | Catechol O-methyltransferase | P21964 | Transferase | 3BWM | 11 | 428 |
7 | ER | Estrogen receptor antagonists | P03372 | Nuclear receptor | 3ERT | 39 | 1388 |
8 | PARP | Poly(ADP-ribose) polymerase | P09874 | Transferase | 4PJT | 33 | 1175 |
9 | SRC | Tyrosine kinase SRC | P12931 | Protein kinase | 2H8H | 155 | 5784 |
10 | VEGFr2 | Vascular endothelial growth factor receptor kinase | P35968 | Transferase | 3VHE | 71 | 2617 |