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Table 3 Summary of the applied protein targets and ligand sets

From: Life beyond the Tanimoto coefficient: similarity measures for interaction fingerprints

  Short name Name Uniprot Protein family PDB code No. actives No. inactives
1 ACE Angiotensin-converting enzyme P12821 Hydrolase 4CA5 49 1727
2 ACHE Acetylcholine esterase P22303 Hydrolase 4M0F 105 3708
3 ALR2 Aldose reductase P15121 Oxidoreductase 4XZH 26 917
4 AR Androgen receptor agonists P10275 Transcription factor 4OEA 64 2234
5 CDK2 Cyclin dependent kinase 2 P24941 Protein kinase 1AQ1 48 1763
6 COMT Catechol O-methyltransferase P21964 Transferase 3BWM 11 428
7 ER Estrogen receptor antagonists P03372 Nuclear receptor 3ERT 39 1388
8 PARP Poly(ADP-ribose) polymerase P09874 Transferase 4PJT 33 1175
9 SRC Tyrosine kinase SRC P12931 Protein kinase 2H8H 155 5784
10 VEGFr2 Vascular endothelial growth factor receptor kinase P35968 Transferase 3VHE 71 2617