From: A visual approach for analysis and inference of molecular activity spaces
Target protein name | PCooA | KMDS | SM | t-SNE | ||||
---|---|---|---|---|---|---|---|---|
AUC | MCC | AUC | MCC | AUC | MCC | AUC | MCC | |
Sigma non-opioid intracellular receptor 1 (Sigma1R) | 0.87(*) | 0.63 | 0.80 | 0.60 | 0.79 | 0.55 | 0.79 | 0.47 |
Histamine H1 receptor (HRH1) | 0.80 | 0.45 | 0.83 | 0.43 | 0.78 | 0.36 | 0.87(*) | 0.54 |
Potassium voltage-gated channel subfamily H member 2 (HERG) | 0.80 | 0.18 | 0.77 | 0.24 | 0.80 | 0.25 | 0.89(*) | 0.33 |
D(1B) dopamine receptor (DRD5) | 0.98(*) | 0.77 | 0.86 | 0.32 | 0.80 | 0.42 | 0.90 | 0.41 |
Overall performance (average score) | 0.86 | 0.51 | 0.82 | 0.40 | 0.79 | 0.40 | 0.86 | 0.44 |