Fig. 6From: Identifying new topoisomerase II poison scaffolds by combining publicly available toxicity data and 2D/3D-based virtual screeningThe structure of human Top2\({\upbeta }\) is shown with purple color in cartoon, while ligands are shown in stick representation. Co-crystallized structure of mitoxantrone is marked in red color, while poses of NSC317921 and NSC637992 obtained by Glide SP docking calculations are colored using atom typesBack to article page