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Table 8 Stability data for the training set compounds involved in ‘positive’ and ‘no shift’ transformations

From: Predicting liver cytosol stability of small molecules

Transform ID # Training examples Avg. t1/2 [min] (left) Avg. t1/2 [min] (right) Avg. of Δ t1/2 [min]
T2 53 20.7 ± 33.4 83.0 ± 47.0 32.0
T4 3 20.8 ± 9.8 116.2 ± 6.6 94.9
T5 1 19.2 ± 0.0 > 120.0 N/A
T6 3 24.4 ± 5.1 > 120.0 95.5
T7 2 4.0 ± 0.0 96.7 ± 33.0 89.7
  1. The geometric mean of Δ t1/2 is provided in addition to the average of t1/2 of compounds on left and right