Fig. 6

Comparison between density plots of V1B and MacrolactoneDB for molecular properties: a MW—molecular weight, b MolLogP—calculated water/octanol partition coefficient, c TPSA—topological polar surface area, d HBA—hydrogen bond acceptors, e HBD—hydrogen bond donors, f NRB—rotatable bonds. Green rectangles indicate values within druglike regions based on Lipinski and Veber’s rules