Table 1 Activity classes
From: Activity landscape image analysis using convolutional neural networks
ChEMBL target ID | Target name | No. compounds | Potency [pKi] | IQR (Q1–Q3) | |
|---|---|---|---|---|---|
Min | Max | ||||
CHEMBL204 | Coagulation factor II | 1099 | 1.00 | 12.19 | 5.30–7.47 |
CHEMBL205 | Carbonic anhydrase 2 | 2701 | 0.60 | 11.10 | 6.24–8.04 |
CHEMBL214 | Serotonin receptor 1A | 1936 | 0.36 | 10.85 | 6.74–8.29 |
CHEMBL217 | Dopamine D2 receptor | 3427 | 2.85 | 10.57 | 6.29–7.49 |
CHEMBL218 | Cannabinoid receptor 1 | 1938 | 3.79 | 10.10 | 5.95–7.62 |
CHEMBL219 | Dopamine D4 receptor | 1086 | 4.74 | 10.52 | 6.43–7.87 |
CHEMBL222 | Sodium-dependent noradrenaline transporter | 1000 | 2.26 | 9.52 | 5.86–7.54 |
CHEMBL224 | Serotonin receptor 2A | 1967 | 3.51 | 11.00 | 6.56–8.12 |
CHEMBL225 | Serotonin receptor 2C | 1085 | 3.51 | 9.70 | 6.23–7.70 |
CHEMBL226 | Adenosine receptor A1 | 2829 | 4.12 | 12.23 | 5.87–7.14 |
CHEMBL229 | Alpha-1A adrenergic receptor | 594 | 4.04 | 10.44 | 6.90–8.40 |
CHEMBL233 | Mu-type opioid receptor | 2009 | 4.20 | 11.80 | 6.37–8.33 |
CHEMBL234 | Dopamine D3 receptor | 2518 | 4.17 | 10.00 | 6.79–8.40 |
CHEMBL236 | Delta-type opioid receptor | 1604 | 3.72 | 10.68 | 6.00–8.08 |
CHEMBL237 | Kappa-type opioid receptor | 1853 | 4.09 | 11.52 | 6.45–8.49 |
CHEMBL238 | Sodium-dependent dopamine transporter | 850 | 2.14 | 9.40 | 5.60–7.37 |
CHEMBL240 | Potassium voltage-gated channel subfamily H_2 | 1053 | 3.89 | 9.55 | 5.29–6.44 |
CHEMBL245 | Muscarinic acetylcholine receptor M3 | 609 | 4.11 | 10.30 | 6.70–9.10 |
CHEMBL251 | Adenosine receptor A2a | 3305 | 3.92 | 11.38 | 6.05–7.67 |
CHEMBL253 | Cannabinoid receptor 2 | 2605 | 0.63 | 10.72 | 6.24–7.99 |
CHEMBL255 | Adenosine receptor A2b | 1265 | 3.37 | 9.80 | 6.30–7.82 |
CHEMBL256 | Adenosine receptor A3 | 2567 | 1.32 | 11.00 | 6.16–7.84 |
CHEMBL261 | Carbonic anhydrase 1 | 2657 | 0.56 | 11.00 | 5.34–7.09 |
CHEMBL264 | Histamine H3 receptor | 2323 | 4.07 | 10.60 | 7.21–8.70 |
CHEMBL344 | Melanin-concentrating hormone receptor 1 | 1187 | 3.57 | 9.77 | 6.90–8.01 |
CHEMBL1800 | Corticotropin-releasing factor receptor 1 | 673 | 4.26 | 9.66 | 6.58–8.14 |
CHEMBL1833 | 5-hydroxytryptamine receptor 2B | 695 | 5.00 | 9.96 | 6.13–7.40 |
CHEMBL2014 | Nociceptin receptor | 839 | 4.40 | 10.70 | 7.09–8.52 |
CHEMBL3155 | 5-hydroxytryptamine receptor 7 | 1111 | 3.30 | 10.00 | 6.53–7.95 |
CHEMBL3242 | Carbonic anhydrase 12 | 2008 | 3.08 | 9.62 | 6.92–8.23 |
CHEMBL3371 | 5-hydroxytryptamine receptor 6 | 2134 | 1.38 | 10.40 | 7.03–8.52 |
CHEMBL3594 | Carbonic anhydrase 9 | 2347 | 1.34 | 9.92 | 6.61–8.04 |
CHEMBL3759 | Histamine H4 receptor | 887 | 2.85 | 10.40 | 5.98–7.59 |
CHEMBL4005 | Serine/threonine protein kinase PIK3CA | 882 | 4.65 | 10.52 | 7.01–8.46 |
CHEMBL4550 | Arachidonate 5-lipoxygenase-activating protein | 1318 | 5.60 | 9.40 | 6.75–8.21 |
CHEMBL4792 | Orexin receptor type 2 | 1444 | 4.96 | 10.15 | 6.13–7.57 |
CHEMBL5071 | Prostaglandin D2 receptor 2 | 794 | 4.48 | 10.00 | 6.49–8.41 |
CHEMBL5113 | Orexin receptor type 1 | 1249 | 4.19 | 9.80 | 5.47–7.19 |