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Table 4 LigTMap prediction on the 250 decoys for the 5 protein targets from the benchmark target classes

From: LigTMap: ligand and structure-based target identification and activity prediction for small molecular compounds

Intended target Top 1 Top 5 Top 10 Fail %Top-10 %Fail
Beta secretase I 2 9 14 36 28% 72%
Bromodomain IV 3 14 21 29 42% 58%
Carbonic anhydrase II 0 2 3 47 6% 94%
HIV Reverse transcriptase 0 1 1 49 2% 98%
Kinase PLK1 0 1 2 48 4% 96%