Table 4 LigTMap prediction on the 250 decoys for the 5 protein targets from the benchmark target classes
Intended target | Top 1 | Top 5 | Top 10 | Fail | %Top-10 | %Fail |
|---|---|---|---|---|---|---|
Beta secretase I | 2 | 9 | 14 | 36 | 28% | 72% |
Bromodomain IV | 3 | 14 | 21 | 29 | 42% | 58% |
Carbonic anhydrase II | 0 | 2 | 3 | 47 | 6% | 94% |
HIV Reverse transcriptase | 0 | 1 | 1 | 49 | 2% | 98% |
Kinase PLK1 | 0 | 1 | 2 | 48 | 4% | 96% |