ELECTRA-DTA: a new compound-protein binding affinity prediction model based on the contextualized sequence encoding

Table 9 Results of ablation experiments

Dataset	method	CI	MSE	R	\(r_m^2\)	AUPR
Davis	ELECTRA-DTA	0.896 (0.002)	0.195	0.838	0.637 (0.048)	0.685 (0.026)
Davis	Onehot-DTA	0.850 (0.005)	0.301	0.739	0.525 (0.018)	0.561 (0.029)
KIBA	ELECTRA-DTA	0.892 (0.002)	0.143	0.892	0.780 (0.014)	0.805 (0.005)
KIBA	Onehot-DTA	0.883 (0.002)	0.157	0.881	0.744 (0.012)	0.792 (0.003)
BindingDB	ELECTRA-DTA	0.837 (0.002)	0.650	0.860	0.670 (0.027)	0.811 (0.001)
BindingDB	Onehot-DTA	0.830 (0.001)	0.700	0.849	0.659 (0.037)	0.799 (0.004)

ISSN: 1758-2946