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Table 6 Most significant proteins, which are more often downregulated by the mostDILI than the noDILI group

From: KNIME workflow for retrieving causal drug and protein interactions, building networks, and performing topological enrichment analysis demonstrated by a DILI case study

Uniprot_ID

Gene_name

Significance_score

P23219

PTGS1

16.0

O60656

UGT1A9

14.0

O94956

SLCO2B1

11.0

Q92887

ABCC2

9.0

P11509

CYP2A6

9.0

P22309

UGT1A1

7.5

Q9Y694

SLC22A7

7.0

P05177

CYP1A2

6.0

Q9NPD5

SLCO1B3

6.0

Q9Y6L6

SLCO1B1

6.0

P11712

CYP2C9

5.8

P02763

ORM1

5.0

P35503

UGT1A3

5.0