Fig. 7
From: PIKAChU: a Python-based informatics kit for analysing chemical units
Comparison of PIKAChU to various other chemical drawing software packages. A SmilesDrawer, ChemDraw, RDKit and PIKAChU drawings given the SMILES string ‘C/C=C(\N)/C’. While ChemDraw, RDKit and PIKAChU all draw the cis–trans stereochemistry of the double bond correctly, with the amino group cis of the methyl group, SmilesDrawer draws the stereobond in the wrong orientation. B SmilesDrawer, ChemDraw, RDKit and PIKAChU drawings of the heavily cyclised molecule vancomycin. C SmilesDrawer, ChemDraw, RDKit and PIKAChU drawings of the molecule aplasmomycin B, D epicolactone, and E paclitaxel.