Table 1 Overview of the six transporter datasets which are provided on the LiverTox workspace
From: Using Jupyter Notebooks for re-training machine learning models
Endpoint | LiverTox training | LiverTox test | ||
|---|---|---|---|---|
Actives | Inactives | Actives | Inactives | |
Breast cancer resistance protein (BCRP) | 432 | 542 | 109 | 86 |
Bile salt export pump (BSEP) | 114 | 410 | 43 | 116 |
Organic anion transporting polypeptide 1B1 (OATP1B1) | 178 | 1472 | 64 | 137 |
Organic anion transporting polypeptide 1B3 (OATP1B3) | 116 | 1547 | 40 | 169 |
Multidrug resistance associated protein (MRP3) | 32 | 52 | – | – |
P-glycoprotein (Pgp) | 612 | 549 | 86 | 48 |